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When and why would IVF be recommended?

In-vitro fertilization (IVF) can rather help couples overcome various types of infertility. For some diagnoses or conditions, such as tubal factor, IVF may, in fact, be the first-line treatment. In other cases, IVF may also be recommended in case only a simpler treatment fails.

Tubal Factor (Damage to Fallopian Tubes) / Pelvic Adhesions

There are two options to treat patients with significant tubal damage and/or pelvic adhesive disease. The first option is to surgically repair the tubes and either get pregnant naturally or make use of Artificial Insemination or IUI in order to get pregnant. In many cases, however, surgery is not, of course, a good option as it can be very difficult to surgically fix the damaged tube(s) and/or the surgery may cause a high risk of an ectopic pregnancy. In such instances where the surgical option does not really pose a high chance for success, the second option is actually to by-pass the tubes completely by making use of IVF as the treatment plan.

Endometriosis

Current scientific data about endometriosis does show that mild to moderate forms of endometriosis may indeed be effectively treated with a combination of surgical and medical therapy. For more stages of endometriosis, including the presence of endometriosis, IVF is no doubt optimal first-line treatment and offers the highest pregnancy success rates.

Male Factor Infertility

There have been most significant advances in the treatment of infertility for men with severe sperm abnormalities in order to be able to achieve fertilization of the egg and successful pregnancy. IVF of course in addition of ICSI (Intracytoplasmic Sperm Injection) has indeed enabled couples suffering from abnormal sperm, who would not of course otherwise be able to conceive, to be able to start their family. ICSI treatment in Hyderabad is often recommended in case there is any suggestion of a sperm problem, if sperm is obtained surgically, or if there has rather been a prior failure of fertilization.

Diminished Ovarian Function & Age-Related Infertility

During the course of a woman’s normal reproductive life, her ovarian function decreases with age. In many cases, this does reduce function that can be overcome through the use of IVF alone, or in conjunction with techniques such as Assisted Hatching and ICSI. For some women, this decrease in ovarian function may indeed start at earlier ages and also requires aggressive treatment with IVF sooner rather than later.

Anovulation & Polycystic Ovarian Syndrome (PCOS)

The majority of patients with anovulation and/or PCOS often conceive making use of less aggressive treatments such as ovulation induction with IUI. For some patients who are “high responders” to gonadotropin therapy, IVF does offer an excellent prognosis and also reduce some of the risks of higher order multiples.

Unexplained Infertility

Approximately 20% of couples will indeed have no identifiable cause of infertility after completing a comprehensive evaluation. IVF is often successful even if more of the conservative treatments that have failed, especially since some of these couples may indeed have yet unidentifiable causes of infertility or sub-fertility.

Family Balancing (also known as Gender or Sex Selection)

For families who wish to have additional children of a particular gender having a previous child, PGD does allow for selection of embryos to transfer based on gender. While not perfect, embryo biopsy with genetic chromosome determination prior to transfer of embryos can allow families choice in how they can also expand the family.

Genetic Diseases / Preimplantation Genetic Screening or Diagnosis (PGS or PGD)

IVF is meant to provide genetic testing on embryos prior to implantation. PGD or PGS is made use of for patients who are at risk for passing on genetic disorders to their offspring as a result of one or both of the partners who happen to be carriers for the disease.

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